Lab Equipment

THIEMT delivers and installs all lab devices, which will be needed for a complete lab resp. an extensive quality control.

Starting with the devices for the sample preparation right up to such, which are serving for the result interpretation resp. the product cleaning.

Customer-oriented (all-in-one-)solutions
Co-ordinated components
Large international manufacturer-pool
Full accessory
Special solutions

According to the product-complexity, the configuration takes place in cooperation with the manufacturer.
Below, few sample devices for the different lab divisons.

Technochemical Analysis

Devices, which are used for the material- and purity testings and to the extraction and preparation of chemical products. Serving for the qualitative and quantitative analysis.

Samples: Spectral photometer, devices for the interpretation of nitrogen (e.g. Kjeldahl), density measuring devices, devices for the measurement of conductivity.

Biology and Biotechnology

Devices and systems, which are serving to the enhancement/cultivation, analysis and interpretation of the material of biological origin resp. to the (active) solid production or biotransformation.

Samples: Devices for the PCR-measuring method, incubators, digester.

Chromatography (gr. colour drawing)

Physicochemical method for the separation of the mixture of substances. In the process, the sample, (gas- or liquid mixture) will be brought in a separating system, consisting of a separating segment and 2 none interblending phases. Depending on differently strong interactions, with the flow substance (mobile phase) and the nonemotile (stationary) phase, the single components will be transported on the separating segment, rapidly different. At the end of the separating segment resp. of the separating process, they will be detected (e.g. peak, dyeing) and, if applicable, lagged for additional analysis purposes.

Classification of the chromatography types:

By separating principle: adsorption, distribution (solubility), ionic-exchange, extensive property (molecule strainer), affinity, enantiomer.
Remark: Mostly different separating mechanisms are becoming important at the chromatography.
By aggregate state of the mobile phase: Liquid chromatography, gas chromatography, hypercritical fluid-chromatography.
By geometric design of the separating segment: Columns-, flat base- (planar) and layer chromatography.

Column-Chromatography-Systems, which are often used:

Gas Chromatography (GC): A gaseous resp. undecomposed, vaporable sample will be put on a heated column and will be conducted over liquid- or solid stationary phase by an indifferent carrier gas as a mobile phase. Separation by the boiling point, distribution- and adsorptions forces.; Application: Medicine, biology, food chemistry, environmental analysis, forensic; Sample: Emission control of industrial production facilities; Coupling with mass spectrometer at the metabolite analysis.
High Performance Liquid Chromatography (HPLC): The solution present analytics will be pumped through a column of solid stationary phase, by the flow substance, under high pressure (up to 500 bar). A particle size, smaller 10 µm (stat. phase), raises the separating performance enormously. 80 % of all HPLC are made by RP (reversed phase), a phase anyway, which is covalent against the elution substance.; This method is applied, for example, at the proof of doping substances, like erythropoietin in the blood.

Spectroscopy

The concept of spectroscopy summarizes a class of methods, which are analyzing the interaction of the electromagnetic radiation, by the matter.

As a function of the used wavelengths (e.g. microwave-, infrared,-, vis-, uv-, Roentgen-radiation) resp. the analyzed matter (ions, atoms, molecules), the specific methods will be differenced.

Essentially, the spectroscopy serves to the structural reconnaissance and identification of ions, atoms and molecules.

In addition to the so-called elastic (e.g. x-ray diffraction XRD) and inelastic (e.g. Raman-spectroscopy) scattering, there is a 3. type interaction: The absorption resp. emission of photons/ light quantums. This last type is designated as the „spectroscopy in a proper sense“.

Types of spectroscopy – samples:

Atomic spectroscopy:
- Atomic absorption spectroscopy (AAS)
- Electron spectroscopy
- Gamma spectroscopy
- X-ray spectroscopy
Molecule spectroscopy:
- Fluorescence spectroscopy
- Vibration spectroscopy -> infrared spectroscope a.o.
- Microwave spectroscopy
Laser spectroscopy
Ionic spectroscopy

Effectively, the near-infrared-spectroscopy NIRS, in particular, (wave length range 760 – 2500 nm), combined with the Fourier-transformation, discovers a boost of application. An interferometer, integrated in the spectrometer, provides a so-called interferogram and out of it, the essential spectrum will be calculated, by use of a mathmatic transformation (computerized). Essentially, the shortend measuring times are the benefit.

In- and Online-Systems

Among the in- and online measuring systems, the measurement takes place during the analyses processes, straight at resp. in the reactor/process-environment.

If applicable, the system is directly connected with the process control system.
Advantages opposite offline-analytics:

High information content
Early warning system
Extended flexibility at the device build-up by variable gap between measuring- and processing system.

Disadvantages opposite offline-analytics:

Only few analyses methods applicable: Essentially photometric- and electrochemical methods
Perhaps lower measuring accuracy

Difference between inline- and online-measurement:

Online: Assay (educt, (intermediate)product) will be obtained/ alienated off the process and convicted into a measuring cell. The assay will be condemned afterwards.

Inline (In situ): The probe will be installed directly into the reactor/substancial current or in a bypass. The assay remains in the process. This method is especially suited for toxic/explosive/air- and temperature sensitive substances.

Samples: Online-analyser for the blur measurement, inline-carbon dioxide measuring device.

Packaging Analytics

Devices, which are intended to serve to the quality control of packaging (glass, plastic, metal) and their content. Be proved on integrity and sufficient stability of the packaging material, on correlation between the packaging and the content, on sufficient storability and filling quantity, according to the product information on the packing.

Samples: Oxygen measurement in stuffed bottles and cans, filling quantity control, can fold control, wall thickness measurement, identification of the internal pressure consistency.

Basic Lab Configuration

Electrical devices, vessels, tools and other auxiliaries, which are used in each lab.
Samples: Compartment drier, water bath, Bunsen burner, tripod with a double socket and clamps, magnetic stirrer, jar forcep, Peleus ball, glassware, porcelain mortar.

Consumables

Raw materials and supplies, which are used up in analytical processes resp. adopted in analyses.
Samples: Filter papers, chemicals, Eppendorf-cones, Petri dishes, cannulas, etc.

Biological Culture Media

Substrates, which are serving as a proof for the cultivation of microorganisms (bacteria), cells and tissues.

A distinction is made between liquid culture media, also referred to as nutritional solution and solid breeding grounds.
Beside the essential nutrients (organic resp. inorganic carbon-, nitrogen-, sulfur- and phosphate sources), inorganic salts as well as the gelling agent at solid media, frequently the following substances are contained in variable rates:

Buffer-substances, dyestuffs or their prestages, retardents for other microorganisms, indicators.
The selection of the culture media is only directed to the requirements of the cultivating item/microorganism.

Samples: Agar-Agar, Bouillon

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